PHILIP L. CIMO, M.D.
To the editor: In their recent paper (Ann Intern Med 83:190-196, 1975) Lackner and Karpatkin reported that many patients with the "easy bruising" syndrome have abnormal platelet function, increased percentages of megathrombocytes, and an elevated prevalence of antiplatelet antibody. I agree that the easy bruising in these patients reflects a qualitative platelet defect, but I question whether the defect is the result of an autoimmune process. Most of the patients studied were women of child-bearing age and, unless the target platelets used for platelet antibody testing were autologous, the increased frequency of platelet antibody activity could be explained by the
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CIMO PL. Antiplatelet Antibody. Ann Intern Med. 1975;83:738. doi: 10.7326/0003-4819-83-5-738_1
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Published: Ann Intern Med. 1975;83(5):738.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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