CHARLES Y. C. PAK, M.D.; JUDITH TOWNSEND, R.N.
To the editor: In 1974 Palmer, Nelson, and Bacchus (1) reported that the ratio of serum chloride to phosphorus (Cl/P) was significantly higher in patients with primary hyperparathyroidism than in those with hypercalcemia from other causes. This observation has been
confirmed subsequently (2, 3). The higher value of Cl/P was attributed to the stimulation of renal bicarbonate and phosphate loss by parathyroid hormone. Recently Drago and associates (3) suggested that serum Cl/P might be useful, not only in the differentiation of primary hyperparathyroidism from other causes of hypercalcemia, but also in the diagnosis of primary hyperparathyroidism itself. It was implied
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PAK CYC, TOWNSEND J. Chloride/Phosphorus in Primary Hyperparathyroidism. Ann Intern Med. 1976;85:830. doi: 10.7326/0003-4819-85-6-830
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Published: Ann Intern Med. 1976;85(6):830.
Endocrine and Metabolism, Parathyroid Disorders.
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