IVAN S. LOGIN
To the editor: In reference to the excellent work reported by Jordan and associates (1) I would like to make several points. The elevation of cerebrospinal fluid (CSF) prolactin should more properly be looked on as a nonspecific response to alterations in the serum hormone concentration rather than a manifestation of extrasellar growth of a pituitary tumor.
This is substantiated by the increased CSF prolactin reported in association with conditions of non-neoplastic hyperprolactinemia either naturally occuring—during pregnancy or neonatal life (2), proestrous in rats (3), or iatrogenic—after intravenous prolactin injection into rabbits (3), or in treatment of patients with psychoactive
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LOGIN IS. Spinal Fluid Prolactin. Ann Intern Med. 1977;86:119–120. doi: 10.7326/0003-4819-86-1-119
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Published: Ann Intern Med. 1977;86(1):119-120.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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