PATRICK J. MCCARTHY, M.D.; BARRY M. SHMOOKLER, M.D.; LAWRENCE E. PIERCE, M.D., F.A.C.P.
MCCARTHY PJ, SHMOOKLER BM, PIERCE LE. Fatal Bone-Marrow Pulmonary Emboli in Multiple Myeloma. Ann Intern Med. 1977;86:317-318. doi: 10.7326/0003-4819-86-3-317
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Published: Ann Intern Med. 1977;86(3):317-318.
Bone-marrow pulmonary embolism may, on occasion, be a primary or contributory cause of death (1). A sudden fatal outcome after pulmonary bone-marrow embolization in a patient with multiple myeloma was reported by Knoblich and Kreiner (2), but to our knowledge, no additional instances have been published. This report describes a patient with refractory multiple myeloma complicated by poorly understood recurrent dyspneic episodes with hypoxia. The basis for these episodes became apparent at postmortem examination that showed bilateral multiple embolic myelomatous bone-marrow particles occluding primarily medium and smaller branches of the pulmonary artery.
A 67-year-old black man was admitted to the
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Emergency Medicine, Hematology/Oncology, Pulmonary/Critical Care, Venous Thromboembolism, Multiple Myeloma.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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