ROBERT I. LEVY, M.D.; JOEL MORGANROTH, M.D.
Familial hyperlipoproteinemia was discovered through one of its secondary and inconsistent manifestations, deposits of lipids in skin and tendons, called xanthomatosis. As early as 1873, however, it was suggested that xanthomas might arise from hyperlipidemia, a supposition reinforced by histologic and chemical analyses of xanthomatous lesions in man and experiments in animals (1).
Gofman and colleagues (2) laid the foundation for the study of hyperlipidemia based on lipoprotein analyses. In 1954, using analytical ultracentrifugation they provided the first clear-cut separation by lipoprotein analyses of what they then called "xanthoma tuberosum" from "xanthoma tendinosum." The patient with "xanthoma tendinosum" (now known
Learn more about subscription options.
Register Now for a free account.
LEVY RI, MORGANROTH J. Familial Type III Hyperlipoproteinemia. Ann Intern Med. 1977;87:625–628. doi: 10.7326/0003-4819-87-5-625
Download citation file:
Published: Ann Intern Med. 1977;87(5):625-628.
Cardiology, Coronary Risk Factors, Dyslipidemia.
Results provided by:
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only