STEPHEN J. LERMAN, M.D.; MARCIA R. SILVER, M.D.; GEORGE A. NANKERVIS, PH.D., M.D.
To the editor: In a paper on our 1969 clinical trial of HPV-77:DE-5 live attenuated rubella virus vaccine in adolescent girls and young women (1), we described in detail a 17-year-old vaccinee (subject #281) who developed moderate arthralgia of her knees and hips, moderate-to-severe arthritis of her fingers, and a painful ganglion. We noted that intermittent arthralgia of her knees and hips had persisted for a year after vaccination. We report here an 8-year follow-up.
Subject #281 is now a 25-year-old resident in internal medicine. At 2-to-3-month intervals and in association with the onset of cool, damp weather, she experiences
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LERMAN SJ, SILVER MR, NANKERVIS GA. Arthralgia and Rubella Immunization. Ann Intern Med. 1978;88:131. doi: 10.7326/0003-4819-88-1-131_1
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Published: Ann Intern Med. 1978;88(1):131.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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