BERNARD PLOUVIER, M.D.; BERNARD DEVULDER, M.D.
To the editor: With reference to the letter of K. A. Oster (1), we wish to report a trial of treatment with folic acid, at daily dose of 1 mg/kg body weight during 1 month, in 10 patients with gout (five with hyperuricemia and hyperuricosuria, five with isolated hyperuricosuria).
In one case, an attack of gout developed on the sixth day. Blood uric acid has been determined weekly in the patients with hyperuricemia, and no change was found during the period of folic acid administration. We observed a fall of 10% in urine uric acid excretion during the first week
Learn more about subscription options.
Register Now for a free account.
PLOUVIER B, DEVULDER B. Folic Acid, Xanthine Oxidase, and Uric Acid. Ann Intern Med. 1978;88:269. doi: 10.7326/0003-4819-88-2-269_2
Download citation file:
Published: Ann Intern Med. 1978;88(2):269.
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only