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Four review articles by different authors have the common theme of experimental production of liver disease. The first review, by Zimmerman, is a detailed, well-organized discussion of experimental hepatotoxicity. This review is 120 pages long, with 640 references. It should be of particular interest to hepatologists, pharmacologists, toxicologists, and pathologists. Included are a complete list of known hepatotoxic agents, their chemical properties, and mechanisms of hepatotoxic effects on animals and man.
Mackay's review of liver disease due to infection and allergy lacks depth and organization in some areas—for example, liver infections by parasites, protozoa, fungi and bacteria—but the sections on
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Experimental Production of Diseases.. Ann Intern Med. 1978;88:443. doi: 10.7326/0003-4819-88-3-443_1
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Published: Ann Intern Med. 1978;88(3):443.
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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