CHARLES EIL, M.D., PH.D.; BRUCE T. ADORNATO, M.D.
To the editor: Multifocal eosinophilic granuloma (Hand-Schüller-Christian disease) often produces lytic lesions of the skeletal system. Scintiscanning with bone-seeking agents is thought to be a usually reliable and early means of detecting such lesions (1, 2). We have recently reported (3) the case of a patient with multifocal eosinophilic granuloma who suffered extradural C7 to T1 nerve root compression associated with a radiotomographically demonstrable T1 vertebral body lesion but had a negative technetium-99m-diphosphonate bone scan.
We report here the case of a second patient with extradural spinal root compression with histologically verified multifocal eosinophilic granuloma in whom conventional radiographs, computerized
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EIL C, ADORNATO BT. Caution on Bone Scans in Eosinophilic Granuloma. Ann Intern Med. 1978;89:289. doi: 10.7326/0003-4819-89-2-289_2
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Published: Ann Intern Med. 1978;89(2):289.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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