MARY H. FANG, M.D.; ALLEN L. GINSBERG, M.D.; WILLIAM O. DOBBINS III, M.D.
Flurazepam hydrochloride (Dalmane®), a commonly used hypnotic available since 1970, has not previously been linked with hepatic toxicity (1). We report here the case of a patient with jaundice associated with flurazepam hydrochloride.
A 70-year-old white man was admitted on 5 September 1977 with a 2½-month history of anorexia, weakness, and fatigue. Two and one-half weeks before admission, he had noticed brown urine and clay-colored stools. Pruritis and jaundice had occurred 1 week later. He denied abdominal pain and significant weight loss. A cholecystectomy and an appendectomy had been done in 1969 and coronary artery bypass in 1972. He now
Learn more about subscription options.
Register Now for a free account.
FANG MH, GINSBERG AL, DOBBINS WO. Cholestatic Jaundice Associated with Flurazepam Hydrochloride. Ann Intern Med. 1978;89:363–364. doi: 10.7326/0003-4819-89-3-363
Download citation file:
Published: Ann Intern Med. 1978;89(3):363-364.
Results provided by:
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only