ERNEST N. ARNETT, M.D.; JEFFREY M. ISNER, M.D.; DAVID R. REDWOOD, M.D.; KENNETH M. KENT, M.D.; WILLIAM P. BAKER, M.D.; HAROLD ACKERSTEIN, M.D.; WILLIAM C. ROBERTS, M.D.
Of 10 patients with fatal coronary heart disease undergoing coronary angiography 0 to 69 d (average, 21) before necropsy, the amount of narrowing in 61 coronary arteries observed angiographically (diameter reduction) during life by three angiographers was compared with that observed histologically (cross-sectional area) at necropsy. No overestimations of the degree of narrowing were made angiographically. Of 11 coronary arteries or their subdivisions narrowed 0 to 50% in cross-sectional area histologically, none were underestimated angiographically; of eight narrowed 51% to 75% histologically, seven had been underestimated, and of 42 narrowed 76% to 100% histologically, 17 were underestimated angiographically. The coronary atherosclerotic plaquing was diffuse (> 25% cross-sectional area narrowing) in 90% of 467 five-millimetre segments of coronary artery examined (24 cm per patient), and this diffuseness of the atherosclerotic process seems to be the major reason for angiographic underestimation of coronary narrowings.
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ARNETT EN, ISNER JM, REDWOOD DR, KENT KM, BAKER WP, ACKERSTEIN H, et al. Coronary Artery Narrowing in Coronary Heart Disease: Comparison of Cineangiographic and Necropsy Findings. Ann Intern Med. 1979;91:350–356. doi: 10.7326/0003-4819-91-3-350
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Published: Ann Intern Med. 1979;91(3):350-356.
Cardiology, Coronary Heart Disease.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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