KATHLEEN H. MEADOR, M.D.; ZEEV SHARON, M.D.; EDMUND J. LEWIS, M.D.
Two drug addicts who practiced subcutaneous injection of crushed tripelennamine and pentazocine tablets, a practice known as "skin-popping," developed nephrotic syndrome and demonstrated amyloidosis on renal biopsy. These patients had chronic inflammation of the skin in the form of abscesses and ulcerations. Although both patients were long-standing drug abusers, they had practiced intradermal drug administration for only 3 years. The occurrence of amyloidosis in these patients appears to relate to their particular drug habit and must be considered in the differential diagnosis of proteinuria in this patient population.
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MEADOR KH, SHARON Z, LEWIS EJ. Renal Amyloidosis and Subcutaneous Drug Abuse. Ann Intern Med. 1979;91:565-567. doi: 10.7326/0003-4819-91-4-565
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Published: Ann Intern Med. 1979;91(4):565-567.
Tobacco, Alcohol, and Other Substance Abuse.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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