JEAN PAPE, M.D.; CAROL SINGER, M.D.; TIMOTHY E. KIEHN, Ph.D.; BURTON J. LEE, M.D.; DONALD ARMSTRONG, M.D.
PAPE J, SINGER C, KIEHN TE, LEE BJ, ARMSTRONG D. Infective Endocarditis Caused by Rothia dentocariosa. Ann Intern Med. 1979;91:746-747. doi: 10.7326/0003-4819-91-5-746
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Published: Ann Intern Med. 1979;91(5):746-747.
The genus Rothia was created by Georg and Brown (1) in 1967 to include members of the family Actinomycetaceae that resemble Nocardia and Actinomyces morphologically but differ significantly in their physiology and cell wall constituents. The pathogenicity of Rothia dentocariosa, the prototype organism, was first demonstrated experimentally in mice by Roth and Flanagan (2) in 1969. Although the occurrence of R. dentocariosa in the oral cavity is well established, it has rarely been recognized as a human pathogen. The first reported human infection due to R. dentocariosa was described by Scharfen (3) in 1975 in the case of a periappendiceal
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Cardiology, Endocarditis, Infectious Disease.
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