JEFFREY L. MILLER, M.D.
To the editor: Hematologic side effects are known to occur as rare side effects of most nonsteroidal anti-inflammatory drugs. Pancytopenia or granulocytopenia has been observed with tolmetin sodium, naproxen, phenylbutazone, and indomethacin. To our knowledge, this side effect has not previously been reported with sulindac. We present a case of aplastic anemia apparently associated with use of sulindac.
A 54-year-old white man with classic ankylosing spondylitis also had apical pulmonary fibrosis and mild Addison's disease. For a recent flare of his sacroiliac pain, naproxen, 250 mg twice daily, was prescribed in March 1979 but was of no help and was
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MILLER JL. Marrow Aplasia and Sulindac. Ann Intern Med. 1980;92:129. doi: 10.7326/0003-4819-92-1-129_1
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Published: Ann Intern Med. 1980;92(1):129.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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