JOSEPH F. PLOUFFE, M.D.; ROBERT J. FASS, M.D.
Two patients with culture-negative chronic meningitis were diagnosed as having Histoplasma capsulatum meningitis based on serial serologic studies; both had antibody in the cerebrospinal fluid as well as the serum. The patients were treated successfully with amphotericin B and had favorable clinical responses. Three control patients with active histoplasmosis and positive serum serologic tests, but without meningeal involvement, did not have antibody in the cerebrospinal fluid. Patients with chronic meningitis of obscure cause should have serial serum and cerebrospinal fluid antibody studies for H. capsulatum.
Learn more about subscription options.
Register Now for a free account.
PLOUFFE JF, FASS RJ. Histoplasma Meningitis: Diagnostic Value of Cerebrospinal Fluid Serology. Ann Intern Med. 1980;92:189-191. doi: 10.7326/0003-4819-92-2-189
Download citation file:
Published: Ann Intern Med. 1980;92(2_Part_1):189-191.
CNS Infections, Infectious Disease, Neurology.
Results provided by:
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only