J. L. LEJONC, M.D.; I. MACQUIN, M.D.; P. BROCHARD, M.D.; A. SCHAEFFER, M.D.
LEJONC JL, MACQUIN I, BROCHARD P, SCHAEFFER A. Hypertension in Systemic Necrotizing Vasculitis. Ann Intern Med. 1980;93:150. doi: 10.7326/0003-4819-93-1-150_1
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Published: Ann Intern Med. 1980;93(1_Part_1):150.
To the editor: Drs. White and Schambelan (1) reported in the February 1980 issue two cases of hypertension with hyperreninemia complicating systemic necrotizing vasculitis. In one case, hypertension was easily controlled with captopril during the time that evidence of healing of renal vasculitis was obtained, likely due to cyclophosphamide and prednisone. Therefore, the authors advocated the use of captopril as an effective antihypertensive agent in such patients. Because hypertension was present, however, in the initial stages of the disease, some degree of hypertension control related to improvement in the underlying disease process cannot be fully ruled out. Indeed, Fauci and
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