A. DAMIANO, M.D.; D. ZULAICA, M.D.; E. CUADRADO, M.D.; M. OCHOA, M.D.
DAMIANO A, ZULAICA D, CUADRADO E, OCHOA M. Immunologic Findings in Kawasaki Disease. Ann Intern Med. 1981;94:138-139. doi: 10.7326/0003-4819-94-1-138_2
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Published: Ann Intern Med. 1981;94(1):138-139.
To the editor: Recently, a paper in your journal (1) and a symposium (2) have been devoted to Kawasaki disease. In spite of the vast cumulative data, its pathogenesis remains unclear. Screening for viral infections has been unsuccessful, and a hypersensitivity reaction against an unknown antigen is supported by the inconsistant finding of circulating immune complexes (3, 4), decreased serum levels of C3 and C4, and abnormally high values of serum IgE (5). We found an unusual pattern of IgM and C3 deposits in skin biopsy specimens from a patient with Kawasaki disease.
A 10-year-old boy was hospitalized with a
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