MARY LEE, PHARM.D.; ROWEENA N. SCHWARTZ; ROOHOLLAH SHARIFI, M.D.
To the editor: Recently, cases of warfarin resistance due to unrecognized vitamin K supplementation in liquid nutrition products have been described (1, 2). These reports came coincidentally, as we were managing a patient with apparent anticoagulant resistance due to the same cause. She was a 70-year-old woman who had had pelvic exenteration for carcinoma of the proximal urethra. Over the next 3 weeks she received 3 L of crystalline amino acid solution without vitamin K supplementation, and a 14-day course of chloramphenicol for treatment of Bacteroides fragilis septicemia. During her convalescence she developed an acute episode of deep venous thrombosis
Learn more about subscription options.
Register Now for a free account.
LEE M, SCHWARTZ RN, SHARIFI R. Warfarin Resistance and Vitamin K. Ann Intern Med. 1981;94:140–141. doi: 10.7326/0003-4819-94-1-140_3
Download citation file:
Published: Ann Intern Med. 1981;94(1):140-141.
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only