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The primary purpose of this monograph is to survey recent advances in the biology and biochemistry of human neutrophils with special attention to clinical problems in health and disease. Alterations in neutrophil functions and population, leading to neutropenia during infection and malignancy, are examined. The author ascribes enzymatic deficiencies in the granule contents of neutrophils as indicative of a mechanism leading to susceptibility to infections and precancerous states.
Although the author has thoughtfully outlined many unsolved questions of pathophysiology, many of his references fail to consider contributions after 1975 or 1976. The few references included from after 1976 are primarily
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Human Neutrophils.. Ann Intern Med. 1981;94:423. doi: 10.7326/0003-4819-94-3-423_1
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Published: Ann Intern Med. 1981;94(3):423.
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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