WILLIAM GANZ, M.D.
Supported in part by grant HL17651, Specialized Center of Research.
GANZ W.; Intracoronary Thrombolysis in Evolving Myocardial Infarction. Ann Intern Med. 1981;95:500-502. doi: 10.7326/0003-4819-95-4-500
Download citation file:
Published: Ann Intern Med. 1981;95(4):500-502.
Extensive myocardial necrosis remains the principal cause of death and morbidity among patients hospitalized with acute myocardial infarction. The clinical impact of interventions designed to reduce necrosis by reducing myocardial oxygen demand, augmenting collateral blood supply, or correcting ischemic cellular defects has been disappointing. As a result, the conviction that restoring blood flow to the ischemic myocardium is needed for clinically significant reduction of necrosis is becoming stronger.
The rate of myocardial necrosis is known to differ widely in experimental animals, from virtually no necrosis after several hours of coronary artery occlusion to transmural necrosis after only 40 minutes of
to gain full access to the content and tools.
Learn more about subscription options.
Register Now for a free account.
Cardiology, Emergency Medicine, Acute Coronary Syndromes.
Results provided by:
Copyright © 2016 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only