MURRAY L. COHEN, M.D.; ITZHAK KRONZON, M.D.
Primary pulmonary hypertension is a disease of unknown cause that presents with a progressive rise in pulmonary artery pressure leading almost inevitably to the development of right-sided heart failure and death. This disorder occurs most frequently in women during the second and third decade of life (1, 2).
Increased pulmonary vascular resistance associated with an increased pulmonary artery pressure and normal left-sided pressure form the physiologic basis of the diagnosis (2). The decrease in pulmonary vascular resistance in response to vasodilators seen early in the course of the disease is lost as the disease progresses (3). Wagenvoort and Wagenvoort (1)
Learn more about subscription options.
Register Now for a free account.
COHEN ML, KRONZON I. Adverse Hemodynamic Effects of Phentolamine in Primary Pulmonary Hypertension. Ann Intern Med. 1981;95:591–592. doi: 10.7326/0003-4819-95-5-591
Download citation file:
Published: Ann Intern Med. 1981;95(5):591-592.
Pulmonary Hypertension, Pulmonary/Critical Care.
Results provided by:
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only