STEVEN M. WAGNER, M.D.
To the editor: I read with great interest the paper by Hoofnagle and associates (1). Information on the natural history of type B chronic hepatitis is welcomed by anyone treating patients with chronic liver disease.
I take exception to their recommendations on therapy with corticosteroids in patients with type B hepatitis. Corticosteroids have not been shown to be efficacious in treating type B hepatitis regardless of the severity of histologic changes. A previous paper (2) by many of the same authors as the recent Annals article did recommend treatment with corticosteroids for symptomatic patients who had severe histologic abnormalities and
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WAGNER SM. Seroconversion from Hepatitis B e Antigen in Chronic Type B Hepatitis. Ann Intern Med. 1981;95:656–657. doi: 10.7326/0003-4819-95-5-656
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Published: Ann Intern Med. 1981;95(5):656-657.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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