RUTH L BERKELMAN, M.D.; JOANNE GODLEY, M.D.; JUDITH A. WEBER, M.P.H.; ROGER L ANDERSON, Ph.D.; A. MARTIN LERNER, M.D.; NORMAN J. PETERSEN; JAMES R. ALLEN, M.D.
Use of trade names is for identification only and does not constitute endorsement by the Public Health Service, U.S. Department of Health and Human Services.
▸Requests for reprints should be addressed to Ruth L. Berkelman, M.D.; Hospital Infections Program, Center for Infectious Diseases, Centers for Disease Control; Atlanta, GA 30333.
BERKELMAN RL, GODLEY J, WEBER JA, ANDERSON RL, LERNER AM, PETERSEN NJ, et al. Pseudomonas cepacia Peritonitis Associated with Contamination of Automatic Peritoneal Dialysis Machines. Ann Intern Med. 1982;96:456-458. doi: 10.7326/0003-4819-96-4-456
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Published: Ann Intern Med. 1982;96(4):456-458.
During a 3-month period, Pseudomonas cepacia was recovered from the peritoneal fluid of 10 patients having chronic dialysis therapy at a peritoneal dialysis center. Six patients developed clinical evidence of peritonitis; one patient developed septicemia. Epidemiologic studies showed that dialysis on specific peritoneal dialysis machines was associated with an increased risk of infection. Laboratory investigation showed contamination of two machines with P. cepacia. Inadequacies in the cleaning and disinfection practices of the automatic peritoneal dialysis machines were identified. Cross-contamination between machines probably occurred through the peritoneal fluid discharge from infected patients during dialysis. Also, the intermittent 2-hour exposure of the machine to 2% formaldehyde may have been inadequate. P. cepacia has not been isolated from the peritoneal fluid of any peritoneal dialysis patient after machine cleaning and disinfection practices were altered.
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Gastroenterology/Hepatology, Infectious Disease, Nephrology, Renal Replacement Therapy.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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