JEFFREY P. DAVIS, M.D.; JAMES M. VERGERONT, M.D.; P. JOAN CHESNEY, M.D.
Future research activity in toxic shock syndrome should provide further understanding of the ways different host-defense mechanisms are involved in toxic shock syndrome; such efforts must consider toxic shock syndrome as a toxin-mediated disease. Topics that require further research include Staphylococcus aureus acquisition in relation to toxic shock syndrome; bacterial colonization factors including bacterial adherence, vaginal mucosal alteration, secretory IgA, and indigenous flora; conditions that affect organism growth and toxin production including the presence of iron, the availability of calcium, potential defects in opsonization and neutrophil function, and potential defects in lymphocyte function; and the development of natural antibodies against a suspected toxin associated with toxic shock syndrome.
Learn more about subscription options.
Register Now for a free account.
DAVIS JP, VERGERONT JM, CHESNEY PJ. Possible Host-Defense Mechanisms in Toxic Shock Syndrome. Ann Intern Med. 1982;96:986–991. doi: 10.7326/0003-4819-96-6-986
Download citation file:
Published: Ann Intern Med. 1982;96(6_Part_2):986-991.
Multi-Organ Failure and Sepsis, Pulmonary/Critical Care.
Results provided by:
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only