JUDITH C. AHRONHEIM, M.D.
To the editor: Metoclopramide, a central dopamine receptor antagonist, has potent cholinergic stimulatory effects on the gastrointestinal tract and is used for a variety of motility related symptoms. Reported extrapyramidal side effects of the drug include acute dystonic reactions, parkinsonism, and tardive dyskinesias (1-5), the last two occurring predominantly in the elderly. I report an elderly woman in whom short-term metoclopramide induced an acute extrapyramidal reaction in which essential-type tremor was the predominant feature.
An 86-year-old woman with postprandial belching and abdominal bloating was treated with oral metoclopramide, 10 mg three times a day. Her gastrointestinal symptoms were relieved, but
Learn more about subscription options.
Register Now for a free account.
AHRONHEIM JC. Metoclopramide and Tremor. Ann Intern Med. 1982;97:621. doi: 10.7326/0003-4819-97-4-621_1
Download citation file:
Published: Ann Intern Med. 1982;97(4):621.
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only