E. HARRIS PIERCE, M.D., M.S.; ROBERT DELLAVALLE, PHARM. D.; JAMES WIELENGA, PHARM. D.
PIERCE EH, DELLAVALLE R, WIELENGA J. Raynaud's Disease and Nifedipine. Ann Intern Med. 1983;98:111. doi: 10.7326/0003-4819-98-1-111_1
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Published: Ann Intern Med. 1983;98(1):111.
To the editor: Until recently, no therapeutic regimen for Raynaud's disease has provided consistent results without significant side effects (1). Two recent reports seem to indicate a role for calcium-channel blocking agents in the treatment of this disorder(2, 3). We report the successful use of nifedipine in a patient with Raynaud's disease not responsive to conventional therapy.
A 64-year-old white woman had a 7-year history of bilateral numbness, coldness, and blanching of the distal ends of her index and middle fingers. At the time of diagnosis, no precipitating cause could be identified. Consequently, she was diagnosed as having Raynaud's disease.
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