RUTH A. RABINOVITCH, M.D.; EDMUND H. DUTHIE, M.D.; STEVEN R. GAMBERT, M.D.; BEVERLY PRIEFER, M.S.; MICHAEL W. RYTEL, M.D.
RABINOVITCH RA, DUTHIE EH, GAMBERT SR, PRIEFER B, RYTEL MW. Pneumococcal Antigen and Pneumococcal Infection. Ann Intern Med. 1983;98:113-114. doi: 10.7326/0003-4819-98-1-113_2
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Published: Ann Intern Med. 1983;98(1):113-114.
To the editor: Streptococcus pneumoniae is the commonest cause of bacterial pneumonia in the elderly (1), and many elderly patients are receiving the new pneumococcal vaccine (2). We have been interested in whether pneumococcal antigens in the vaccine could lead to false-positive results when serum and urine samples from vaccine recipients were tested for pneumococcal polysaccharide using counterimmunoelectrophoresis or coagglutination.
We studied 22 residents aged 52 to 92 years at the Wood Veterans Administration Medical Center Nursing Home, after their initial inoculation with pneumococcal vaccine. Blood was drawn 2 to 4 hours and 1 day after vaccination; spontaneously voided urine
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