MORIE A. GERTZ, M.D.; ROBERT A. KYLE, M.D.; PHILIP R. GREIPP, M.D.
Twenty-two of 91 (24%) patients with primary systemic amyloidosis were functionally hyposplenic. This group, identified by blood smear findings, had a different survival distribution when compared with a normosplenic group (p < 0.0001). The peripheral blood smear was more sensitive than the splenic scan for a diagnosis of hyposplenism. Amyloidosis should be included in the differential diagnosis of acquired hyposplenism in the adult.
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GERTZ MA, KYLE RA, GREIPP PR. Hyposplenism in Primary Systemic Amyloidosis. Ann Intern Med. 1983;98:475–477. doi: 10.7326/0003-4819-98-4-475
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Published: Ann Intern Med. 1983;98(4):475-477.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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