SANJEEV PRAKASH, M.D.; NARINDER K MEHRA, PH.D.; ANAND N MALAVIYA, M.D.
To the editor: The frequency of the HLA-B27 antigen in samples of the normal Indian population and its association with ankylosing spondylitis, Reiter's disease, and other spondyloarthropathies is similar to those reported in Western studies. The HLA-B27 antigen has been detected by us in 5.9% of 118 controls, 94% of 51 patients with ankylosing spondylitis (relative risk, 254), 83% of 36 patients with Reiter's disease (relative risk, 79), and 84% of 25 patients with "unclassifiable" seronegative peripheral arthritis (relative risk, 83) (1). This last group of patients are primarily males with seronegative asymmetric arthritis mainly involving large joints of lower
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PRAKASH S, MEHRA NK, MALAVIYA AN. HLA-B27 Homozygosity in Seronegative Spondyloarthropathies. Ann Intern Med. 1983;98:676. doi: 10.7326/0003-4819-98-5-676
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Published: Ann Intern Med. 1983;98(5_Part_1):676.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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