HAROLD W. JAFFE, M.D.; KEEWHAN CHOI, Ph.D.; PAULINE A. THOMAS, M.D.; HARRY W. HAVERKOS, M.D.; DAVID M. AUERBACH, M.D.; MARY E. GUINAN, Ph.D., M.D.; MARTHA F. ROGERS, M.D.; THOMAS J. SPIRA, M.D.; WILLIAM W. DARROW, Ph.D.; MARK A. KRAMER, Ph.D.; STEPHEN M. FRIEDMAN, M.D.; JAMES M. MONROE, M.S.; ALVIN E. FRIEDMAN-KIEN, M.D.; LINDA J. LAUBENSTEIN, M.D.; MICHAEL MARMOR, Ph.D.; BIJAN SAFAI, M.D.; SELMA K. DRITZ, M.D.; SALVATORE J. CRISPI, B.A.; SHIRLEY L. FANNIN, M.D.; JOHN P. ORKWIS, B.S.; ALEXANDER KELTER, M.D.; WILMON R. RUSHING, M.P.H.; STEPHEN B. THACKER, M.D.; JAMES W. CURRAN, M.D., M.P.H.
To identify risk factors for the occurrence of Kaposi's sarcoma and Pneumocystis carinii pneumonia in homosexual men, we conducted a case-control study in New York City, San Francisco, Los Angeles, and Atlanta. Fifty patients (cases) (39 with Kaposi's sarcoma, 8 with pneumocystis pneumonia, and 3 with both) and 120 matched homosexual male controls (from sexually transmitted disease clinics and private medical practices) participated in the study. The variable most strongly associated with illness was a larger number of male sex partners per year (median, 61 for patients; 27 and 25 for clinic and private practice controls, respectively). Compared with controls, cases were also more likely to have been exposed to feces during sex, have had syphilis and non-B hepatitis, have been treated for enteric parasites, and have used various illicit substances. Certain aspects of a lifestyle shared by a subgroup of the male homosexual population are associated with an increased risk of Kaposi's sarcoma and pneumocystis pneumonia.
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JAFFE HW, CHOI K, THOMAS PA, HAVERKOS HW, AUERBACH DM, GUINAN ME, et al. National Case-Control Study of Kaposi's Sarcoma and Pneumocystis carinii Pneumonia in Homosexual Men: Part 1, Epidemiologic Results. Ann Intern Med. 1983;99:145-151. doi: 10.7326/0003-4819-99-2-145
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Published: Ann Intern Med. 1983;99(2):145-151.
Hematology/Oncology, Infectious Disease.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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