LEONARD E. BRAITMAN, PH.D.
Many clinicians and medical researchers are unsure how to interpret data that do not pass tests of statistical significance. Because a nonsignificant result does not imply that there is no effect or no difference, it is important to make "the distinction between positively demonstrating that a treatment had no effect and failing to demonstrate that it does have an effect . . ." (1). In clinical trials, the lack of efficacy of a new treatment sometimes is inferred from a nonsignificant difference between outcomes in treatment and placebo groups. Such inferences are invalid without consideration of the ability of the
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BRAITMAN LE. Statistical Power Analysis in Medical Research. Ann Intern Med. 1983;99:269–271. doi: 10.7326/0003-4819-99-2-269
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Published: Ann Intern Med. 1983;99(2):269-271.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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