FRIEDRICH CONRAD, M.D.; HOLGER BAUMGARTNER, M.D.; CHRISTIAN WIEDERMANN, M.D.; GEORG KLEIN, M.D.
To the editor: Because emotional sweating is under sympathetic control (1), clonidine, known to inhibit sympathetic tone (2), could be useful in the treatment of excessive emotional sweating (hyperhidrosis), a disorder that is still a therapeutic problem (1). Several reports imply a possible inhibition of sweating by clonidine in various conditions, including diabetic gustatory sweating (3, 4). In the summer of 1979, we tested clonidine in six hyperhidrotic patients (three palmar, two plantar, and one axillar) who had considered surgical sympathectomy. Informed consent was obtained before the study.
Intravenous clonidine, 1.8 mg/kg body weight, was tested twice (single blind) in
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CONRAD F, BAUMGARTNER H, WIEDERMANN C, KLEIN G. Clonidine and Hyperhidrosis. Ann Intern Med. 1983;99:570. doi: 10.7326/0003-4819-99-4-570_1
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Published: Ann Intern Med. 1983;99(4):570.
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