FRED ROSENFELT, M.D.; WILLIAM YOUNG, M.D.; STUART LONKEY, M.D.; BARRY ROSENBLOOM, M.D.
ROSENFELT F, YOUNG W, LONKEY S, ROSENBLOOM B. Sarcoidosis Progressing to Lymphoma. Ann Intern Med. 1983;99:878. doi: 10.7326/0003-4819-99-6-878_2
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Published: Ann Intern Med. 1983;99(6):878.
To the editor: Blayney and associates (1) have recently presented their hypothesis on sarcoidosis and human T-cell leukemia-lymphoma virus. An etiologic association between sarcoid and a viral or other agent remains to be proved; we recently saw a patient who may be of interest in this regard.
A 39-year-old white man presented with a 2-year history of lymphadenopathy and pulmonary infiltrates. Prior bronchoscopic examination and samples from two open lung biopsies showed nonspecific inflammation and non-caseating granulomas. In addition, samples from two lymph node biopsies showed reactive hyperplasia with non-caseating granulomas. All bacterial, fungal, and tuberculous cultures were negative. In
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