DEAN J. KEREIAKES, M.D.; MARTIN J. LIPTON, M.D.
KEREIAKES DJ, LIPTON MJ. Diagnosis of Thromboembolic Pulmonary Hypertension. Ann Intern Med. 1983;99:880. doi: 10.7326/0003-4819-99-6-880_1
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Published: Ann Intern Med. 1983;99(6):880.
To the editor: Moser and associates (1) have drawn appropriate attention to difficulties in establishing the diagnosis of chronic thromboembolic pulmonary hypertension. Symptoms or signs of thromboembolic disease may be absent or unrecognized, and recurrent emboli may simulate pneumonia with pleuritis, chronic bronchitis, and coronary, valvular, or congenital heart disease (2). Differentiation from primary pulmonary hypertension is frequently difficult. Noninvasive evaluations often lack specificity for thromboembolic disease, and direct demonstration of pulmonary arterial thrombi has previously been achieved only by angiography.
At the University of California, San Francisco, we have used rapid sequential computed tomographic scanning during the administration of
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