CESAR PRU, M.D.; CARL M. KJELLSTRAND, M.D.; RICHARD A. COHN, M.D.; ROBERT L. VERNIER, M.D.
Nephrotic syndrome recurred in 16 patients who had been free of the disease for an interval of 4 to 25 years. Their initial illness began in childhood and responsed to adrenocorticosteroid therapy; in 10 patients it was associated with few changes on light microscopic examination of kidney biopsy specimens. The late recurrence also responded to steroids, and in only 1 patient did low-grade proteinuria persist after treatment. Renal biopsy specimens taken from 8 patients during late recurrence showed minimal-change nephrotic syndrome in 7 and focal segmental glomerulosclerosis in 1. Renal function remained normal in all patients. The late recurrence of minimal-change nephrotic syndrome has most of the features of that syndrome seen in the more typical childhood age group and should be managed similarly.
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PRU C, KJELLSTRAND CM, COHN RA, VERNIER RL. Late Recurrence of Minimal Lesion Nephrotic Syndrome. Ann Intern Med. 1984;100:69-72. doi: 10.7326/0003-4819-100-1-69
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Published: Ann Intern Med. 1984;100(1):69-72.
Nephrology, Nephrotic Syndrome.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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