GIAN PIERO FASOLA, M.D.; FRANCESCO D'OSUALDO, M.D.; VINCENZO DE PANGHER, M.D.; ENZO BARDUCCI, M.D.
To the editor: Mexiletine, a primary amine that resembles lidocaine in chemical structure, is a new anti-arrhythmic agent without known haematologic side effects. Adverse reactions to the drug include only one case of thrombocytopenia (1). We report the case of a patient who developed thrombocytopenia after mexiletine administration.
On 18 June 1983, a 53-year-old man was hospitalized with heart failure and ischemic heart disease. Two platelet counts obtained 2 weeks and a few days before admission were normal (greater than 200 000/mm3). There was no history of drug allergy or thrombocytopenia, and no evidence of splenomegaly. Body temperature, erythrocyte sedimentation
Learn more about subscription options.
Register Now for a free account.
FASOLA GP, D'OSUALDO F, DE PANGHER V, BARDUCCI E. Thrombocytopenia and Mexiletine. Ann Intern Med. 1984;100:162. doi: 10.7326/0003-4819-100-1-162_1
Download citation file:
Published: Ann Intern Med. 1984;100(1):162.
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only