BERTRAND J. SHAPIRO, M.D.; MELVIN A. WELCH, R.R.T.; PHILIP MERCURIO, R.R.T.
SHAPIRO BJ, WELCH MA, MERCURIO P. The IPPB Trial. Ann Intern Med. 1984;100:457-458. doi: 10.7326/0003-4819-100-3-457_3
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Published: Ann Intern Med. 1984;100(3):457-458.
To the editor: We are greatly disturbed by several points in the article (1) on the trial comparing intermittent positive pressure breathing (IPPB) and compressor nebulizer therapies. Seventy percent of screened candidates were not entered into the study, many because of refusal to participate or recent use of IPPB or compressor nebulizers. Our conjecture is that in these moderately to severely ill patients, most have used either IPPB or compressor nebulizers in the course of their illness. The candidates who were screened but not enrolled in the study may have included responders to the therapies. Responders, when faced with going
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