JAMES L. VACEK, M.D., MAJ.
VACEK JL. Nifedipine and Primary Pulmonary Hypertension. Ann Intern Med. 1984;100:458-459. doi: 10.7326/0003-4819-100-3-458
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Published: Ann Intern Med. 1984;100(3):458-459.
To the editor: The article by Rubin and associates on primary pulmonary hypertension (1) was interesting, and agrees with previously published experience (2, 3). The authors were appropriately cautious in describing their results, as many drugs have shown differing short- and long-term benefits in this syndrome (4, 5), without clear improvement in patient survival.
Only five of the nine patients in this study had sustained benefit from nifedipine treatment. Mean follow-up in the six patients with an initial favorable response was only 7.3 months, which in view of the variable course of the disease may not be adequate to show
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