MARCOS A. SOUZA LIMA, M.D.
Ranitidine (Zantac; Glaxo, Incorporated, Research Triangle Park, North Carolina) is a relatively new H2-receptor antagonist with a potency fourfold to eightfold that of Cimetidine. The debate on the comparative values of these two drugs has intensified (1-3). Minor side effects, such as headaches, skin rash, and dizziness, occur in about 3% of patients receiving ranitidine, but serious toxicity is rare. I report a case of hepatitis occurring after the use of ranitidine.
A 77-year-old woman was hospitalized for fever, chills, nausea, and occasional vomiting. Twelve days before admission she had begun taking ranitidine, 150 mg twice daily, for treatment of
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SOUZA LIMA MA. Hepatitis Associated with Ranitidine. Ann Intern Med. 1984;101:207-208. doi: 10.7326/0003-4819-101-2-207
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Published: Ann Intern Med. 1984;101(2):207-208.
Gastroenterology/Hepatology, Liver Disease.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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