ALBERT C. STRICKLER, M.D.; PAMELA C. KIBSEY, M.D.; HILLAR VELLEND, M.D.
STRICKLER AC, KIBSEY PC, VELLEND H. Seroconversion Rates with Hepatitis B Vaccine. Ann Intern Med. 1984;101:564. doi: 10.7326/0003-4819-101-4-564_1
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Published: Ann Intern Med. 1984;101(4):564.
To the editor: We compliment Dienstag and colleagues (1) on their timely study of the use of hepatitis B vaccine in hospital personnel. With a 97% seroconversion rate, one could reasonably omit postimmunization testing for surface antibody (anti-HBs) and be confident that most recipients have been protected.
The hepatitis B vaccine program at Toronto General Hospital (2) began in January 1983. To date we have completed the series of three injections of Heptavax-B (Merck Sharp & Dohme, West Point, Pennsylvania), 1.0 mL (20 µg) intramuscularly, according to the manufacturer's directions (November 1983), in more than 250 persons. They include employees
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