HOWARD POSNER, M.D.
To the editor: The report of Swartz and colleagues (1) deserves comment. The authors state, "Oral intake of large doses of ascorbic acid has been shown to increase oxalate excretion to levels of 60 to 622 mg/d, implying metabolic conversion of ingested ascorbic acid to oxalate ranging from 2.5% to 30% on a molar basis." They cite four studies as a source for these values. However, three of these studies used an inferior nonspecific method for measuring urinary oxalate. Only the study of Schmidt and coworkers (2) used the new, more specific isotachophoresis technique for oxalate analysis (SCHMIDT KH, HAGMAIER
Learn more about subscription options.
Register Now for a free account.
POSNER H. Ascorbic Acid and Urinary Oxalate. Ann Intern Med. 1984;101:571-572. doi: 10.7326/0003-4819-101-4-571_2
Download citation file:
Published: Ann Intern Med. 1984;101(4):571-572.
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only