JOHN H. GILLIAM III, M.D.; KIM R. GEISINGER, M.D.; JOEL E. RICHTER, M.D.
Epidemiologic evidence of an association between hepatitis B virus and hepatocellular carcinoma is strong, but evidence of a similar association between non-A, non-B hepatitis virus infection and hepatocellular carcinoma is less clear. Reports from Japan (1-3) and Nigeria (4) suggest that hepatitis B serum markers are negative in 5% to 28% of patients with hepatocellular carcinoma. We describe the case of a patient with well-documented chronic non-A, non-B hepatitis acquired after a transfusion who developed hepatocellular carcinoma 9 years later.
A 63-year-old white man was hospitalized in November 1983 with weakness, anorexia, and weight loss of 3 weeks' duration. He
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GILLIAM JH, GEISINGER KR, RICHTER JE. Primary Hepatocellular Carcinoma After Chronic Non-A, Non-B Post-Transfusion Hepatitis. Ann Intern Med. 1984;101:794–795. doi: 10.7326/0003-4819-101-6-794
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Published: Ann Intern Med. 1984;101(6):794-795.
Gastroenterology/Hepatology, Gastrointestinal Cancer, Hematology/Oncology, Infectious Disease, Liver Cancer.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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