SONJA L. SCHOEPPEL, M.D.; RICHARD T. HOPPE, M.D.; RONALD F. DORFMAN, M.D.; SANDRA J. HORNING, M.D.; ANN C. COLLIER, M.D.; TERRENCE G. CHEW, M.D.; LAWRENCE M. WEISS, M.D.
SCHOEPPEL SL, HOPPE RT, DORFMAN RF, HORNING SJ, COLLIER AC, CHEW TG, et al. Hodgkin's Disease in Homosexual Men with Generalized Lymphadenopathy. Ann Intern Med. 1985;102:68-70. doi: 10.7326/0003-4819-102-1-68
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Published: Ann Intern Med. 1985;102(1):68-70.
The syndrome of persistent, generalized lymphadenopathy not attributable to an identifiable cause in homosexual men was first described in 1982 (1). Biopsy samples of the enlarged lymph nodes have shown a characteristic pattern of follicular or paracortical hyperplasia, or both (2, 3). These studies have suggested that this unexplained lymphadenopathy in homosexual men, the lymphadenopathy syndrome, may be part of the spectrum of the acquired immunodeficiency syndrome.
We have recently noted Hodgkin's disease developing in patients with the lymphadenopathy syndrome. This finding is provocative because Hodgkin's disease and the lymphadenopathy syndrome are both associated with cellular immunodeficiencies (4-6). Also, these
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