RICHARD Y. FEIBELMAN, M.D.; ELOISE M. HARMAN, M.D.
FEIBELMAN RY, HARMAN EM. Sarcoid Meningoencephalitis Treated with High-Dosage Steroids and Radiation. Ann Intern Med. 1985;102:136. doi: 10.7326/0003-4819-102-1-136_1
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Published: Ann Intern Med. 1985;102(1):136.
To the editor: The incidence of neurologic involvement in sarcoidosis is reported as 5% to 7% (1, 2). Seizures occur in 5% to 18% of these patients and are associated with a combined morbidity and mortality of 75% (3). The response to steroid and anticonvulsant therapy is variable but generally poor, with most patients having chronic, poorly controlled seizures or progressing to death. We report the case of a patient with stage I pulmonary sarcoidosis complicated by sarcoid meningoencephalitis with seizures. The patient's course was progressive despite steroid treatments in high doses, and he began to show improvement only after
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