WILLIAM B. HARWELL, M.D.
To the editor: Hyperimmunoglobulin E syndrome, or Job's syndrome, consists of recurrent pyogenic infections (usually staphylococcal), elevated levels of IgE, eczema, a cellular defect in chemotaxis, and sometimes, peripheral blood eosinophilia (1). Although both urticaria (2) and anaphylaxis (3), manifestations of systemic mastocytosis, have been described in association with this syndrome, their association has not been well described. We describe the case of a patient who has features of both the hyperimmunoglobulin E syndrome and systemic mastocytosis.
In June 1977 a 32-year-old white woman sought medical attention for a particularly severe episode of pruritus. Physical findings included chronic and generalized
Learn more about subscription options.
Register Now for a free account.
HARWELL WB. Mastocytosis and the Hyperimmunoglobulin E Syndrome. Ann Intern Med. 1985;103:641. doi: 10.7326/0003-4819-103-4-641_1
Download citation file:
Published: Ann Intern Med. 1985;103(4):641.
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only