JAY A. GOLDSTEIN, M.D.
GOLDSTEIN JA. Cimetidine, Ranitidine, and Epstein-Barr Virus Infection. Ann Intern Med. 1986;105:139. doi: 10.7326/0003-4819-105-1-139_2
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Published: Ann Intern Med. 1986;105(1):139.
To the editor: Patients with chronic Epstein-Barr virus infection (1) might be relieved to have their syndrome diagnosed but are usually discouraged when told there is no recognized effective therapy, because their symptoms are often disabling. I have treated ten such patients, who had dysfunction from 9 months to 15 years. All had antibody to Epstein-Barr early antigen in titers of 1:40 or greater. Because of my success in treating acute mononucleosis with cimetidine (2), I decided to try cimetidine or ranitidine on these patients.
In the usual doses prescribed for treatment of peptic ulcer disease, every one of these
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