KEVIN E. VITTING, M.D.; NORMAN J. NICHOLS, M.D.; GENE R. SELIGSON, M.D.
VITTING KE, NICHOLS NJ, SELIGSON GR. Naproxen and Acute Renal Failure in a Runner. Ann Intern Med. 1986;105:144. doi: 10.7326/0003-4819-105-1-144_1
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Published: Ann Intern Med. 1986;105(1):144.
To the editor: We recently treated a 41-year-old male marathon runner who developed acute renal failure after taking a nonsteroidal anti-inflammatory drug.
The patient was an advertising writer in excellent condition, and his prior history was remarkable only for borderline hypertension. For 1 week before the marathon he had been taking naproxen, 250 mg three times daily, until 36 hours before the race.
During the 17th mile of the race he dropped out with severe cramping, nausea, and fever. Two days later he was hospitalized with oliguric acute renal failure. He appeared well nourished and well hydrated. His temperature was
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