PAUL BANNISTER, M. D., M.R.C.P.; PETER SHERIDAN, M.D., M.R.C.P.; JOHN DIBBLE, M.D.; R. BRIAN PAYNE, M.D.
BANNISTER P, SHERIDAN P, DIBBLE J, PAYNE RB. Benign Hypercalcemia and "Benign Hypocalcemia" in the Same Family. Ann Intern Med. 1986;105:217-219. doi: 10.7326/0003-4819-105-2-217
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Published: Ann Intern Med. 1986;105(2):217-219.
Familial benign hypercalcemia, first described in 1972 by Foley and colleagues (1), is an autosomaldominant condition characterized by asymptomatic hypercalcemiawithout hypercalciuria. Its clinical and pathogenetic features have been reviewed recently (2). We
describe results of a study in another family with benign hypercalcemia, some of whose second-generation offspring were found to have hypocalcemia.
A 51-year-old woman had cervical spondylosis and C5 root compression. Biochemical screening showed the following serum concentrations: calcium, 2. 77 mmol/L; inorganic phosphate, 1.08 mmol/L; and albumin, 44 g/L. Repeated serum calcium estimations ranged from 2.72 to 2.84 mmol/L. Serum parathyroid hormone concentrations were normal.
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Endocrine and Metabolism, Fluid and Electrolyte Disorders, Nephrology.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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