VINCENT P. BUTLER JR., M.D.; THOMAS W. SMITH, M.D.
If inadvertently the doses of the Foxglove should be prescribed too largely, exhibited too rapidly, or urged to too great a length, the knowledge of a remedy to counteract its results would be a desirable thing. Such a remedy may perhaps in time be discovered.
Withering, 1785 (1)
It seemed not out of the question that non-antigenic poisons after combination with protein would call forth antibodies capable of neutralizing their toxic effect. This idea . . . would hold out hopes for practical application.
Landsteiner, 1945 (2)
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BUTLER VP, SMITH TW. Immunologic Treatment of Digitalis Toxicity: A Tale of Two Prophecies. Ann Intern Med. 1986;105:613–614. doi: 10.7326/0003-4819-105-4-613
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Published: Ann Intern Med. 1986;105(4):613-614.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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