HIDEJI NAKAMURA, M.D.; MASAFUMI KOGA, M.D.; BUNZO SATO, M.D.; KEIZO NOMA, M.D.; YASUHIKO MORIMOTO, M.D.; SUSUMU KISHIMOTO, M.D.
NAKAMURA H, KOGA M, SATO B, NOMA K, MORIMOTO Y, KISHIMOTO S. Von Recklinghausen's Disease with Pheochromocytoma and Nonmedullary Thyroid Cancer. Ann Intern Med. 1986;105:796-797. doi: 10.7326/0003-4819-105-5-796_2
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Published: Ann Intern Med. 1986;105(5):796-797.
To the editor: It is well known that von Recklinghausen's disease is inherited as an autosomal dominant trait and is often associated with various neoplasms, including pheochromocytoma and nonmedullary thyroid cancer (1, 2). Recently, several cases of "nonmedullary" thyroid cancer have been reported in coexistence with pheochromocytoma (3, 4). We report the case of a patient with von Recklinghausen's disease who also had papillary adenocarcinoma of the thyroid gland and pheochromocytoma, which occurred with some familial disposition.
A 58-year-old woman, who had had café au lait spots and neurofibromas since the age of 30 years, was hospitalized with headache and
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